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ABSTRACT:
Clinical Gaseous Microemboli Assessment of an Oxygenator with Integral Arterial Filter in the Pediatric Population. JECT 2009; 41:226-230. Preston TJ, et al.
The authors determined the CAPIOX® FX15 Oxygenator was as effective in gaseous microemboli removal as was the more traditional oxygenator.
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ABSTRACT:
Clinical Evaluation of the Terumo Capiox® FX05 Hollow Fiber Oxygenator with Integrated Arterial Line Filter; JECT 2009; 41:220-225. Deptula J, et al.
In a comparison study, the authors found the CAPIOX® FX05 Oxygenator offers good gas exchange capabilities and a low pressure drop along with the safety of an integrated arterial line filter.
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ABSTRACT:
Beneficial Effects of Modern Perfusion Concepts in Aortic Valve and Aortic Root Surgery. Perfusion 2009;24: 37-44, Kutschka, et al.
In this 170-patient study, the use of the ROCSafe™ Hybrid Perfusion System was found to reduce side effects of standard extracorporeal circulation.
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ABSTRACT:
Bloodless Cardiac Surgery and the Pediatric Patient: A Case Study. Perfusion 2008; 23: 131-134. Ging, AL et al.
The authors present blood management strategies in which a 5.9 kg Jehovah's Witness patient underwent successful correction of a VSD without the use of transfusions.
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ABSTRACT:
A New Minimized Perfusion Circuit Provides Highly Effective Ultrasound Controlled Deairing. Artificial Organs. 2007 Mar; 31(3):215-220, Kutschka, et al.
This study compared a ROCSafe™ Hybrid Perfusion System to conventional perfusion circuit and results indicated that active venous deairing was significantly reduced compared to passive deairing on a conventional circuit.
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ABSTRACT:
Optimizing Circuit Design Using a Remote-mounted Perfusion System. JECT 2009;41:28-31. Kulat, et al.
In this 62-patient pediatric study, the authors found that use of remotely mounted pump heads resulted in reduced priming volumes and less exposure to banked blood.
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ABSTRACT:
Summary of Select Studies on Air Bubble Removal
Several studies indicate that gaseous microemboli in the extracorporeal circuit is a clinical concern; some demonstrate an association between GME and neurological damage or other organ failure after cardiac surgery.
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ABSTRACT:
A New Poly-2-Methoxyethylacrylate-Coated CPB Circuit Possesses Superior Platelet Preservation and Inflammatory Suppression Efficacy. Annals of Thoracic Surgery. 2004; 77:1678-1683 Ikuta T, et al.
This study compares the biocompatibility of PMEA-coated circuits to heparin-coated and non-coated circuits, focusing on platelet preservation and systemic inflammatory response.
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ABSTRACT:
Investigation of Blood Compatibility of PMEA-Coated Extracorporeal Circuits. Journal of Bioactive and Compatible Polymers, Vol 17, Sept 2002. Kocakulak M, et al.
In a study comparing PMEA-coated and uncoated oxygenators, the authors found greater retention of clotting factors and platelets and less post-op hemorrhaging when using PMEA-coated oxygenators.
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ABSTRACT:
Evaluation of a New Condensed Extracorporeal Circuit for Cardiac Surgery: A Prospective Randomized Clinical Pilot Study. Perfusion 2005; vol. 20, 91-99. Fransen, et al.
The authors noted an improvement in biocompatibility in a reduced prime circuit with Xcoating over a traditional circuit with heparin-coating.
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ABSTRACT:
Emerging Technologies in Biocompatible Surface Modifying Additives: Quest for Physiologic CPB. Cardiovascular and Hematological Agents. 2004; Vol. 2:No 4. Gunaydin S, et al.
The authors compare surface coatings, including Xcoating, in 155 CPB cases for chemical composition, biomaterial evaluation and clinical efficacy.
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ABSTRACT:
The CAPIOX RX05 Oxygenator: Pediatric Clinical Observations. Perfusion. 2003;18, 321-323, Tinius, et al.
The authors provide clinical observations on the use of the CAPIOX® BABY RX™ Oxygenator and reducing prime volume in neonate circuits.
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ABSTRACT:
Biocompatibility of Poly (2-methoxyethylacrylate) Coating for Cardiopulmonary Bypass. Annals Thoracic Cardiovascular Surgery, 2003, Volume 9, No 1. Noguchi, et al.
The authors compare the biocompatibility of PMEA-coated and heparin-coated circuits by measuring several inflammatory markers. Results indicate PMEA-coated circuits are as biocompatible as heparin coated circuits.
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ABSTRACT:
How Effective are Cardiopulmonary Bypass Circuits at Removing Gaseous Microemboli? JECT:2002;34:34-39. Stump D, et al.
This paper demonstrates how the quantity of venous air passed through a circuit differs by circuit design and manufacturer under both VAVD and gravity conditions.
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ABSTRACT:
Clinical Evaluation of Poly (2-methoxyethylacrylate) in Primary Coronary Artery Bypass Grafting. JECT 2005;37:23-31. Vang SN, et al.
The study demonstrates that the use of Xcoating™ compared to no coating results in lower WBC counts, less blood transfusions, and a cost savings of $83.41 per patient.
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ABSTRACT:
Xcoating: A New Biopassive Polymer Coating. Canadian Perfusion Canadienne, Volume 11, No 2, June 2001. Schiel, et al.
This paper explains the mechanism and benefits of Xcoating.
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ABSTRACT:
An Evidence-Based Review of the Practice of Cardiopulmonary Bypass in Adults: a Focus on Neurologic Injury, Glycemic Control, Hemodilution and the Inflammatory Response. J Thorac Cardiovasc Surg2006;132:283-290. Shann KG, et al.
The authors, members of the International Consortium for Evidence-Based Perfusion, offer their first publication of evidence and recommendations on the practice of managing patients on CPB.
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