ABSTRACT:
Leukocyte Filtration and Aprotinin: Synergistic Anti-Inflammatory Protection. Perfusion 2004; Volume 19. O-Yurvati A.
In this follow-up study, Albert O-Yurvati, DO, compares the effects of leukocyte filtration combined with aprotinin versus aprotinin alone to reduce post-operative atrial fibrillation in patients undergoing CPB.
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ABSTRACT:
Intraoperative Treatment Strategy to Reduce the Incidence of Post-Cardiopulmonary Bypass Atrial Fibrillation. Perfusion 2002; V 17. O-Yurvati A.
In this study, the authors demonstrate a 72% reduction in the incidence of post-op atrial fibrillation in patients who receive leukocyte filtration and aprotinin, resulting in $8,725 savings per patient.
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ABSTRACT:
Non-Pharmacologic Therapeutic Strategies for Reducing Complications of Cardiopulmonary Bypass. Filtration 2005; 1(2):95-106. Gunaydin S, et al.
This study of 225 patients undergoing CPB concludes that the use of circuits with leukocyte filtration and X Coatingâ?¢ provides clinically significant benefits for high risk patients.
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ABSTRACT:
Neutrophil Depletion Reduces Myocardial Reperfusion Morbidity. Annals of Thoracic Surgery. March 2004; 77: 956-961. Palatianos, et al.
In this study of 160 patients, the authors demonstrated that neutrophil filtered blood cardioplegia significantly reduced biochemical markers of myocardial reperfusion injury.
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ABSTRACT:
Evaluation of Leukocyte-Depleted Terminal Blood Cardioplegia Solution in Patients Undergoing Elective and Emergency Coronary Artery Bypass Grafting. Journal of Thoracic and Cardiovascular Surgery. 1994;108, 6:1125-3. Sawa, et al.
The authors demonstrate leukocyte-depleted terminal blood cardioplegia provides superior myocardial protective effects in patients undergoing aortic cross-clamping for more than 120 minutes.
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ABSTRACT:
Modifying Risk for Extracorporeal Circulation: Trial of Four Anti-inflammatory Strategies. Annals of Thoracic Surgery, 1998; 66:747-754. Gott, et al.
This 400-patient study of patients undergoing CPB show a reduced length of stay and reduced hospital charges up to $6,000 in low risk patients who receive leukocyte filtration.
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ABSTRACT:
Clinical Evaluation of a Leuko-Depleting Blood Cardioplegia Filter (BC1B) for Elective Open-Heart Surgery. Perfusion 1998; 13: 205-210. Suzuki, et al.
In this study of 40 CABG patients, the authors demonstrate the ability of the Pall BC1 filter to remove inflammatory mediators CPK-MB and troponin.
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