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Shukri F. Khuri, MD
Professor of Surgery, Harvard Medical School, Boston, Mass.
Chief of Surgery, VA Boston Healthcare System, West Roxbury, Mass.
Vice Chairman, Dept. of Surgery, Brigham and Women's Hospital, Boston,
Mass.
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A Career in Translational Research
Dr. Khuri's interest in pH-guided myocardial management began in the mid 1970s
as a quest to identify a metabolic indicator of intra-operative myocardial ischemia.
By 1983, he had identified tissue acidosis as a reliable quantifier of the
magnitude of regional myocardial tissue ischemia. In 1987, he received FDA
clearance for an early version
of a myocardial pH monitoring system that he used to validate his findings
and develop the maneuvers that form the basis of pH-guided myocardial management.
In addition to his work in myocardial protection, Dr. Khuri has also initiated
and led efforts within the Veterans Administration (VA) that resulted in the
establishment of the National Surgical Quality Improvement Program (NSQIP),
the first national, validated, outcome-based, risk-adjusted and peer-controlled
program for the measurement and enhancement of the quality of surgical care
. That program has become the model for a joint effort between the VA and the
American College of Surgeons, led by Dr. Khuri, to establish an NSQIP that will
incorporate data from the non-VA sector of healthcare for the nationwide comparative
assessment and improvement of the quality of all surgical care1.
Throughout the course of his career, Dr. Khuri has achieved national and international
prominence. His research laboratory at West Roxbury has been continuously funded
for 24 years and has trained more than 60 residents and postgraduate students in applied
research. He is a member of numerous professional organizations, including the
prestigious American Surgical Association, and the author of more than 200 peer-
reviewed publications. He is a regular reviewer for more than 10 scientific journals
and has served on the editorial board of the Journal of Thoracic and Cardiovascular
Surgery. His work has been recognized with numerous awards, including the Frank Brown Berry
Prize in 1998.
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