In 2000, we introduced our first biocompatible coating for products used in cardiopulmonary bypass. X Coating™ is an amphiphilic, biopassive coating that reduces protein denaturation and platelet adhesion. This non-heparin coating for the perfusion circuit addresses the goal of heart teams everywhere – to achieve a tip-to-tip coated circuit and improve the biocompatibility of cardiopulmonary bypass.

Developed at Shonan Center, our world-class research and development facility in Kanagawa, Japan, X Coating is now applied to perfusion circuit products at the point of manufacture at our facilities around the world.

X Coating’s benefits have led to its adoption in cardiac ORs around the world. It is biopassive and has no contraindications for patient size. It is indicated for heparin-sensitive patients.

Importantly for future product development, X Coating can be applied to all device material surfaces, including polypropylene, polycarbonate, stainless steel, filter mesh and PVC.